Now and again, I run across a news article or psychological question that is so big that it bleeds out of straight statistics and requires a thorough understanding of the research methodology that guides statistical choices.
When that happens, I email my buddy and fellow W.W. Norton author, Beth Morling, and we write a joint blog post.
Recently, I emailed her because research on using psychedelics to treat many different mental disorders has been in the news. President Trump fast-tracked this research, and the Journal for the American Medical Association recently published a big meta-analysis on the topic.
Psychedelic research has always interested me because of psychology, but it has always amused me because of how you run a proper double-blind research study if your experimental participants KNOW that they are hallucinating and your control group participants know they are not?
This broader question offers a few great discussion options for you and your students as you work through it.
In our co-authored blog post, Beth got into the nitty-gritty of how researchers create comparable control groups to work around this unique research problem. For my part, I wrote about the statistics for comparing two groups (high vs. not-high), as well as participants in the control group versus microdosing versus large-dose. Also, as you will learn, one control group used in this research is people on antidepressants. Which take a while to kick in. So how do you study multiple groups at multiple times?
Read more at Beth's post: https://everydayresearchmethods.com/2026/06/testing-psychedelics-whats-the-control-group/
