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Showing posts with the label animal research

Not a particularly statsy example, but still delightful.

I mean. This is the most entertaining research methodology I have ever seen. What did this look like? This is what it looked like.  So, this is barely a statsy example, but it does include data outcomes:  n = 175, with some snakes striking the boot ( n = 6) and some coiling ( n = 3). While PIs might try to No IRB would let you get away with asking your graduate student to step on snakes. Mostly, this is funny. I found his research, too . While I think the fake leg is highly amusing, I think it is great that Morris is a passionate advocate for snake education and teaching people to be tolerant of snakes they find in the wild. Finally, I heard about this research on an NPR story about snake handling classes (taught by Morris) in Arizona. A WHOLE CLASS. 

Use recent gel nail:cancer headlines to discuss research design

 Many of my students love a good manicure.  Sometimes, they come in with full-on talons.  The youth love manicures.  As such, the recent viral headlines about gel nail polish lamps and cancer matter to them.  #scicomm But what did the original research really study? https://www.nature.com/articles/s41467-023-35876-8#Sec12 (CHECK OUT THIS GREAT RM IMAGE FROM THE ORIGINAL RESEARCH!!!) This  short NPR story by Rachel Treisman  is a great summary. The NPR audio story is accompanied by a written report. In that report, Treisman succinctly summarizes the methodology: https://www.npr.org/2023/01/26/1151332361/gel-nails-cancer-manicure-safe 1. Let's talk about science communication. The NPR story is accurate science reporting. However, most of the headlines don't mention that a) some of the evidence came from mice cells, and they measured cell mutations but not cancer.  2. Let's talk about factorial ANOVA The researchers used a 3 (cell types: human 1, hu...

9% of Americans think they could beat a crocodile in a fight. What?

 https://today.yougov.com/topics/lifestyle/articles-reports/2021/05/13/lions-and-tigers-and-bears-what-animal-would-win-f Sorry that I haven't been posting as often lately. You would think that with the summer, I would have more flexibility, but I am working hard on some writing deadlines (for a stats textbook!), and my kids' activities have picked up considerably with soccer season starting. This example illustrates fun data visualizations as well as a t-test. YouGov is a polling company, sort of like Gallup. They collect many Very Serious polls and silly polls like  this one, where they asked participants to state whether or not they could beat 34 different animals (from rats to grizzly bears) in an unarmed fight. Their graphic designer deserves a raise for this bar graph, including several tragic humans vs. animal memes/movie clips. Here are a few lessons you can draw out of this funny data. Paired t-test example: They took the participants identified as men and women and...

Dvorsky's "Lab Mice Are Freezing Their Asses Off—and That’s Screwing Up Science"

This example can be used to explain why the smallest of details can be so important when conducting research. This piece by Dvosrsky summarizes a recently published  article that points out a (possible!) major flaw in pre-clinical cancer research using rats. Namely, lab rats aren't being kept at an ideal rat temperature. This leads to the rats behaving differently than normal to stay warm: They eat more, they burrow more, and their metabolism changes. The researchers go on to explain that there are also plenty of other seemingly innocuous factors that can vary from rat lab to rat lab, like bedding, food, exposure to light, etc. and that these factors may also effect research findings. Why is this so important? Psychology isn't the only field dealing with a replicability crisis: Rat researchers are also experiencing difficulties. Difficulties that may be the result of all of these seemingly tiny differences in lab rats that are used during pre-clinical research. I thin...

Bichell's "A Fix For Gender-Bias In Animal Research Could Help Humans"

This news story demonstrates that research methods are both federally monitored and that best practices can change over time. For a long time, women were not used in large scale pharmaceutical trials. Why did they omit women? They didn't want to accidentally exposed pregnant women to new drugs and because of fears that fluctuations in females hormones over the course of a month would affect research results. Which always makes me think of this scene from Anchorman: But I digress. This has been corrected for and female participants are being included in clinical trials. But many of the animal trials that occur prior to human trials still use mostly male animals. And, again, policies have changed to correct for this. This NPR story details the whole history of this sex bias in research. Part of why this bias has been so detrimental to women is because women report more side effects to drugs than do men. So, by catching such gender differences earlier with animal models, the...